What is APS?

Autologous Protein Solution (APS) is the latest, novel and Innovative Regenerative Injection therapy to treat pain and slow the progression of cartilage degradation and destruction in Knee Osteoarthritis. (It was initially indicated for treating knee osteoarthritis only, due to its outstanding results, now it is also being approved for its use to treat osteoarthritis in other joints.

Autologous Protein Solution Injection Therapy Treatment in Hadapsar, Pune

APS contains anti-inflammatory cytokines and anabolic growth factors. A treatment gap exists when considering solutions for osteoarthritic pain. There are only a few well researched and clinically proven treatment options between conservative care and the more invasive implant solutions that can relieve the patient’s pain and potentially delay the need for joint replacement surgery.

FAQ’s

How Does APS Injection Work?

In osteoarthritis of the knee, inflammatory cytokines (bad proteins) are in higher concentrations than anti-inflammatory cytokines (good proteins). This imbalance leads to inflammation and gradual degeneration of the knee cartilage.

APS contains concentrated anti-inflammatory cytokines, which inhibit the activity of inflammatory cytokines in the osteoarthritic knee. This reduces inflammation and slows down or halts the degeneration of the knee cartilage.
It is also rich in anabolic cytokines, which stimulate the synthesis of the cartilage matrix.
Reducing inflammation and stimulating repair of the damaged cartilage tissue helps slow down or reverse the progression of osteoarthritis.

Compared to traditional osteoarthritis treatment methods, APS has many benefits. These include:

  • It is a non-invasive procedure involving a single injection.
  • Significantly reduces inflammation and pain (70% reduction) associated with knee arthritis for up to two years.
  • Significantly improves mobility in the treated knee.
  • Protects cartilage from catabolic degeneration
  • Promotes cartilage cell proliferation(Natural Healing)
  • It is an autologous treatment, which eliminates the risk of adverse reactions.

APS injection is used to relieve the symptoms of mild to moderate knee osteoarthritis. Patients with severe osteoarthritis cannot benefit from this treatment as their knee cartilages are almost, if not entirely, degenerated.

APS is a biologic treatment administered to patients suffering from mild to moderate knee osteoarthritis. Compared to keyhole surgery, APS is a non-invasive procedure with minimal to no downtime, and it can be performed within an hour. For patients with moderate osteoarthritis, keyhole surgery cannot help much with their condition, but APS tends to slow, halt, or reverse osteoarthritis progression. As a non-invasive and autologous procedure, APScarries few risks, unlike surgery. In severe cases, however, APS cannot be used in place of total knee replacement as it’s not practical.

APS and PRP injections are similar in that both are autologous treatments that utilize blood proteins to promote tissue healing. The key difference between the two is that contains leukocytes and anti-inflammatory cytokines, which are not present in PRP injections. Also, unlike PRP, which requires several injections to attain desirable results,is a one-time injection providing results that typically last between 1 to 2 years.

As an autologous solution, it is obtained by separating white blood cells and platelets from your blood and concentrating them in a small volume of plasma, using the APS kit.
During the procedure, our specialist draws blood from your arm and separates it to obtain a concentrated APS solution. The entire procedure may take around 20 to 30 minutes to complete. This solution (about 3ml) is then injected into the osteoarthritic knee. During injection, you may experience a minor pinch and discomfort.

After the treatment, it’s normal to experience some knee pain and stiffness, which subsides after about 2 days. After the treatment, one should minimize physical activities for the next 14 days to increase the efficacy of the APS injection. Osteoarthritis pain starts to decrease in approximately one to two weeks following the APS injection. After a few weeks, pain and discomfort are alleviated, and the attained results last for approximately 12-24 months. Although this treatment is one of the best in the industry, it is still not a cure for osteoarthritis

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